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Clinical Trials: Infectious Disease

The Taft Center for Clinical Research is currently conducting clinical trials in multiple areas of medicine, including Infectious Disease.

First-In-Human Study To Evaluate Safety, Tolerability, And Pharmacokinetics of PF-07304814 In Hospitalized Participants With COVID-19.

Study Type/Phase: 1b
Status: Recruiting

The purpose of this study is to evaluate the safety, effectiveness, and dosing of an investigational drug called PF-07304814 for SARS-CoV-2 infection. This is a Phase 1 trial that will occur in...

Remdesivir (RDV; GS-5734) for the Treatment of Selected Coronavirus (CoV) Infection, Single Patient Protocol

Study Type/Phase: Emergency Investigational New Drug
Status: Not Recruiting

An experimental treatment called Remdesivir was provided on a compassionate-use basis to patients hospitalized with COVID-19, an illness caused by infection with SARS-CoV-2...

First-In-Human Study To Evaluate Safety, Tolerability, And Pharmacokinetics of PF-07304814 In Hospitalized Participants With COV

Study Type/Phase: 1b
Status: Recruiting

The purpose of this study is to evaluate the safety, effectiveness, and dosing of an investigational drug called PF-07304814 for SARS-CoV-2 infection. This is a Phase 1 trial that...

Study of Frozen Plasma, PBMCs, and Nasal Swabs from Active COVID-19 Patients

Study Type/Phase: Specimen Collection
Status: Not Recruiting

The purpose of this study is to prospectively collect blood and nasal swabs from willing participants with an active COVID-19 diagnosis. These specimens will...

iSpecimen Network Protocol: Collection and Distribution of Remnant and research Use Only Biospecimens for Rapid Assay Development

Study Type/Phase: Specimen Collection
Status: Not Recruiting

A company called iSpecimen is contracting with hospitals, medical centers, and other healthcare organizations to collect and distribute...

A Phase 3 Randomized Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants with Moderate COVID-19 Compared to Standard of Care Treatment (GS-US-540-5774)

Study Type/Phase: Phase 3
Status: Not Recruiting

The purpose of this study is to evaluate the safety and effectiveness of an investigational drug called Remdesivir (RDV) for COVID-19. There are no approved medications to treat COVID-19...

A Phase 3 Randomized Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants with Severe COVID-19 (GS-US-540-5773)

Study Type/Phase: Phase 3
Status: Not Recruiting

The purpose of this study is to evaluate the safety and effectiveness of an investigational drug called Remdesivir (RDV) for COVID-19. There are no approved medications to treat COVID-19...

Expanded Access to Convalescent Plasma for the Treatment of Patients with COVID-19

Study Type/Phase: Expanded Access Program
Status: Recruiting

The purpose of this study is to provide access to investigational convalescent plasma for patients who have severe or life-threatening COVID-19, or who are at high risk of progression to severe or life-threatening disease. Currently...

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