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Management of Acute Stroke Patients on Treatment with New Oral Anticoagulants: Addressing Real-world Anticoagulant Management Issues in Stroke (ARAMIS) Registry

Phase: Registry
Status: Not Recruiting

The goal of the ARAMIS registry is to capture a large, representative population of stroke patients with either, Acute Ischemic Stroke (AIS), or Intracranial Hemorrhage (ICH), while taking home oral anticoagulant therapy. An Acute Ischemic Stroke occurs when a blood clot forms in a blood vessel causing a sudden loss of blood circulation to an area of the brain as well as a loss of neurologic function. An Intracranial Hematoma occurs when a blood vessel ruptures in the brain or between the skull and the brain, resulting in the compression of brain tissue. Researchers will use the information collected from these patients’ hospitalizations and follow-up telephone interviews to try to address several key treatment and management issues surrounding patients with either condition on anticoagulant therapy. This registry will be fully observational and will not involve investigational treatment or influence management strategies for physicians or patients.

The study will involve up to 2,500 participants, and may be conducted at up to 125 hospitals and medical facilities. El Camino expects to enroll approximately 100 participants at this site.

Speak with your doctor to determine whether you meet the following criteria for participation in this study.

Inclusion Criteria Exclusion Criteria
  • Age 18 or older
  • Diagnosed with acute ischemic stroke and have been treated with dabigatran, rivaroxaban, apixaban, edoxaban within 7 days prior to admission
  • Diagnosed with intracerebral hemorrhage and have been treated with warfarin or one of the new oral anticoagulants within 7 days prior to admission
  • Patients who were transferred from another hospital or discharged to other acute care facility will be excluded

Principal Investigator

Jenelle Jindal, MD


Duke Clinical Research Institute

NCT Number



Sherril Hopper, Neurovascular Nurse Practitioner, Stroke Program Coordinator
El Camino Hospital – Neuroscience Institute
650 988-7831

For more information about this clinical trial, including trial status, eligibility and full trial listing, visit

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