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Clinical Trials: Cardiology

The Taft Center for Clinical Research is currently conducting clinical trials in multiple areas of medicine, including Cardiology.

Clinical Trial to Evaluate Cardiovascular Outcomes in Patients Treated with the Tricuspid Valve Repair System Pivotal (TRILUMINATE Pivotal)

Study Type/Phase: Pivotal, Randomized, Single Arm
Status: Recruiting

The tricuspid heart valve separates the right lower heart chamber (the right ventricle) from the right upper heart chamber (right atrium)...

Transcatheter Aortic Valve Replacement (TAVR) in Patients with the Medtronic Transcatheter Aortic Valve Replacement System in Patients at Low Risk for Surgical Aortic Valve Replacement (SAVR) Continued Access Trial

Study Type/Phase: Prospective, non-randomized, continued access trial
Status: Not Recruiting

Open heart surgery, or surgical aortic valve replacement (SAVR), is the standard treatment for patients with severe aortic stenosis who are at low predicted risk for experiencing major complications...

Comparison of non-invasive vs. invasive hemodynamic measurements Phase II

Study Type/Phase: Feasibility
Status: Recruiting

Heart Failure (HF) is a clinical syndrome caused by structural and functional...

CyberHeart’s cardiac arrhythmia ablation treatment: Patients with Refractory Ventricular Tachycardia / Fibrillation

Study Type/Phase: Pilot
Status: Not Recruiting

Ventricular Tachycardia (VT) is a pathological cardiac rhythm originating...

The Evaluation and Treatment of Elevated Left-Sided Filling Pressures by Balloon Inflation Within the Inferior Vena Cava

Study Type/Phase: Observational
Status: Not Recruiting

This research study will enroll patients suffering from hearth failure who range from mild symptoms...

Living a Low Salt Life Style – Heart Failure Education

Study Type/Phase: Nursing Research Study
Status: Recruiting Inpatients and Cardiac Rehabilitation Patients

The lack of adherence to a low sodium diet in heart failure patients may be correlated with insufficient education regarding...

Safety and Effectiveness Trial for the Nanostim Leadless Pacemaker

Phase: III
Status: Not Recruiting

The purpose of this study is to evaluate the safety and effectiveness of the leadless pacemaker system in treating patients with a slow heart rate or irregular heartbeats. The Nanostim leadless pacema...

Surface ECG and Sensor Data Acquisition of HF Recovery

Study Type/Phase: Feasibility
Status: Recruiting

Heart Failure (HF) affects 5.8 million patients in the United States and 23 million globally...

Amplatzer Amulet Left Atrial Appendage Occluder Randomized Controlled Trial

Phase: Pivotal
Status: Not Recruiting

This research study examines the most common sustained heart rhythm disorder, known as non-valvular atrial fibrillation (AF) and its effects of increased risk of stroke and systemic embolism or blood clots blocking an artery. ...

Barostim neo® – Baroreflex Activation Therapy® for Heart Failure (BeAT-HF)

Phase: Pivotal
Status: Not Recruiting

The purpose of this study is to determine whether the Barostim Neo System device is safe and effective in people with heart failure ...

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT)

Phase: III
Status: Not Recruiting

The COAPT Trial is studying the MitraClip device in heart failure patients with functional mitral regurgitation to whom the local heart team will not offer mitral valve surgery as a treatment option. ...

COAPT Continued Access Study (CAS)

Study Type/Phase: III
Status: Not Recruiting

The COAPT Continued Access Study (CAS) is an extension of an initial trial...

EVOLVE Short DAPT – 3 Month Dual Antiplatelet Therapy (DAPT) with SYNERGYTM Stent System

Study Type/Phase: Interventional
Status: Not Recruiting

The purpose of this study is to to assess the safety of 3-month dual antiplatelet therapy (DAPT) in subjects at high risk for bleeding ...

Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI)

Phase: II/III
Status: Not Recruiting

The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical ...

Transcatheter Aortic Valve Replacement with the Medtronic Transcatheter Aortic Valve Replacement System in Patients at Low Risk for Surgical Aortic Valve Replacement

Phase: Pivotal
Status: Not Recruiting

This research study examines the disease of the aortic valve known as aortic stenosis. ...

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