Clinical Trials: Cardiology
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Watchman FLX versus NOAC for the Embolic Protection in the Management of Patients with non-Valvular Atrial Fibrillation (Champion-AF)
Study Type/Phase: Prospective, Randomized, Multi-center Global Investigation
Status: Not Recruiting
This research study addresses a common sustained heart rhythm disorder known as non-valvular atrial fibrillation (AF). Atrial fibrillation affects your heart’s ability to pump blood normally, causing blood...
Clinical Trial to Evaluate Cardiovascular Outcomes in Patients Treated with the Tricuspid Valve Repair System Pivotal (TRILUMINATE Pivotal)
Study Type/Phase: Pivotal, Randomized, Single Arm
Status: Recruiting
The tricuspid heart valve separates the right lower heart chamber (the right ventricle) from the right upper heart chamber (right atrium)...
Transcatheter Aortic Valve Replacement (TAVR) in Patients with the Medtronic Transcatheter Aortic Valve Replacement System in Patients at Low Risk for Surgical Aortic Valve Replacement (SAVR) Continued Access Trial
Study Type/Phase: Prospective, non-randomized, continued access trial
Status: Not Recruiting
Open heart surgery, or surgical aortic valve replacement (SAVR), is the standard treatment for patients with severe aortic stenosis who are at low predicted risk for experiencing major complications...
Comparison of non-invasive vs. invasive hemodynamic measurements Phase II
Study Type/Phase: Feasibility
Status: Recruiting
Heart Failure (HF) is a clinical syndrome caused by structural and functional...
Living a Low Salt Life Style – Heart Failure Education
Study Type/Phase: Nursing Research Study
Status: Recruiting Inpatients and Cardiac Rehabilitation Patients
The lack of adherence to a low sodium diet in heart failure patients may be correlated with insufficient education regarding...
Safety and Effectiveness Trial for the Nanostim Leadless Pacemaker
Phase: III
Status: Not Recruiting
The purpose of this study is to evaluate the safety and effectiveness of the leadless pacemaker system in treating patients with a slow heart rate or irregular heartbeats. The Nanostim leadless pacema...
Amplatzer Amulet Left Atrial Appendage Occluder Randomized Controlled Trial
Phase: Pivotal
Status: Not Recruiting
This research study examines the most common sustained heart rhythm disorder, known as non-valvular atrial fibrillation (AF) and its effects of increased risk of stroke and systemic embolism or blood clots blocking an artery. ...
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT)
Phase: III
Status: Not Recruiting
The COAPT Trial is studying the MitraClip device in heart failure patients with functional mitral regurgitation to whom the local heart team will not offer mitral valve surgery as a treatment option. ...
Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI)
Phase: II/III
Status: Not Recruiting
The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical ...
Transcatheter Aortic Valve Replacement with the Medtronic Transcatheter Aortic Valve Replacement System in Patients at Low Risk for Surgical Aortic Valve Replacement
Phase: Pivotal
Status: Not Recruiting
This research study examines the disease of the aortic valve known as aortic stenosis. ...